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KMID : 0665420200350060553
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Korean Journal of Food Culture
2020 Volume.35 No. 6 p.553 ~ p.568
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Association between Intake of Food and Cognitive Impairment: A Systematic Review and Meta-analysis
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Kim Yoo-Gyeong
Kim Kyung-Hee
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Abstract
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This systematic review and meta-analysis aimed to determine whether food intake is effective in preventing diseasesrelated to cognitive impairment. We searched English databases namely MEDLINE, PubMed and ScienceDirect from 2000to May 2020, and Korean databases namely RISS, KISS, and DBPIA from 1990 to May 2020. We divided the data into 15groups using the food group classification of the Korean Nutrition Society (KNS). The effect size (Cohen’s d) was estimatedusing a random-effect model, and a 95% confidence interval was calculated for each study. We included 17 cross-sectionalstudies and 7 cohort studies which involved 45,115 participants. As a result of analyzing the subgroups in the Asianpopulation of both sexes, it was observed that grain intake has a protective effect against cognitive impairment. For females,pulses and fish also have a protective role against cognitive impairment. In the case of seaweed, a negative relationship wasfound with a moderate protective effect against cognitive impairment (Cohen’s d:-0.533, 95% CI: -0.939, -0.126; p=0.010)in Korean studies. Dairy products are associated with an increased risk of cognitive impairment in the American andEuropean population but drinking alcohol is associated with a lower impairment risk. These results provide a basis forformulating the dietary guidelines for preventing dementia for each country.
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KEYWORD
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Food, cognitive impairment, meta-analysis, systematic review
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